Original contributionCarboxyhemoglobin levels in patients with flu-like symptoms
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Cited by (48)
Carbon Monoxide Toxicity
2022, Emergency Medicine Clinics of North AmericaThe neurotoxicology of carbon monoxide - Historical perspective and review
2016, CortexCitation Excerpt :Some studies have attempted to address the issue of missed diagnosis by measuring COHb levels in all patients who attend emergency departments with non-specific symptoms. Two small observational trials screening for CO exposure (Balzan, Cacciottolo, & Mifsud, 1994; Dolan, Haltom, Barrows, Short, & Ferriell, 1987) and two large, good quality, prospective observational trials (Clarke et al., 2012; Suner et al., 2008) revealed that up to three quarters of cases go undiagnosed in the community. Suner looked at all admissions to an American University Hospital Emergency department and was able to obtain a COHb level on 75% of admissions; some 10,856 patients in total.
Effect of temperature on CO sensing response in air ambient by using zno nanorod-gated AlGaN/GaN high electron mobility transistors
2013, Sensors and Actuators, B: ChemicalCitation Excerpt :The CO is a product of incomplete combustion of organics due to insufficient oxygen being present to convert carbon into carbon dioxide (CO2), and is mostly produced by the automobiles, industrial processes, cooking equipment or any fireplace. There is a strong affinity of CO for hemoglobin in humans (230–260 times higher than oxygen) [1], and exposures of CO ambient of over 100 parts per million (ppm) can be dangerous to human health [2]; the brain and heart may also be injured with carboxyhemoglobin (COHb) levels exceeding 20% in the blood [3]. However, more evidence has recently been reported that CO can be neuroprotective after ischemic brain injury, depending on its concentration [4].
Accuracy of noninvasive multiwave pulse oximetry compared with carboxyhemoglobin from blood gas analysis in unselected emergency department patients
2011, Annals of Emergency MedicineCitation Excerpt :However, COHb analyzers are not ubiquitously available.11 As a result, many victims of CO poisoning might be overlooked and misdiagnosed.12,13 Conventional pulse oximetry uses 2 different wavelengths of light only and is not able to explicitly determine COHb or methemoglobin levels, leading to wrong results.14
Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department with Acute Carbon Monoxide Poisoning
2008, Annals of Emergency MedicineCitation Excerpt :Estimates of diagnosed nonfatal poisoning cases vary widely, from 15,000 to 40,000 events per year.3,4 However, because misdiagnosis of CO poisoning is common, the true numbers are likely much higher.5,6 The mechanisms of toxicity of CO poisoning are not completely understood.