Summary
The main objective was to assess the biological effect of styrene and methyl methacrylate on the respiratory system in the industrial population. A total of 454 males from the exposed group and 683 workers from the control group were examined. The health status of the workers was evaluated by standardized interviews on chest symptoms and lung function testing. The environmental measurements were performed in all work places where the persons under study were employed.
There was practically no differences in the prevalence of chronic chest symptoms in both groups of workers but the frequency of lung obstruction appeared to be more than twice as high among the exposed persons in comparison with the controls. A large proportion of cases with lung obstruction did not show any chronic chest symptoms. It appeared from the study that the environmental factor developed a much more harmful effect on lung function than smoking, and one effect was independent of the other.
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References
Chmielewski J, Renke W (1975) Clinical and experimental studies on the pathogenesis of toxic effects of styrene. II. The effect of styrene on the respiratory system. Bull Inst Mar Trop Med Gdynia 26:299–302
Elmes PC (1981) Relative importance of cigarette smoking in occupational lung disease. Brit J Ind Med 38:1–13
Fleiss JL (1973) Statistical methods for rates and proportions. J Wiley and Sons, New York
Gross P, Rinehart WE, De Treville PP (1967) The pulmonary reaction to toxic gases. Am Ind Hyg Ass J 28:315–321
Härkönen H (1978) Styrene, its experimental and clinical toxicology. A review. Scand J Work Environ Health [Suppl 2] 4:194–214
Jedrychowski W (1979) Considerations of risk factors and development of chronic bronchitis in a five-year follow-up study of an industrial population. J Epid Community Med 33:210–214
Jedrychowski W, Flak E (1980) Standard normal spirometric values of FVC, FEV1, FEF25-50-75% and FEF200-1200 in a random sample of healthy non-smokers (in Polish). Przeg Lek 37:643–646
Lorimer WV, Lilis R, Nicholson WJ, Anderson H, Fischbein A, Daum S, Rom W, Rice C, Selikoff TJ (1976) Clinical studies of styrene workers: initial findings. Environ Health Perspect 17:171–181
Medical Research Council (1965) Definitions and classification of chronic bronchitis for clinical and epidemiological purposes. Lancet 1:775–777
Medical Research Council (1966) Questionnaire on respiratory symptoms and instructions for its use. MRC, London
Sawicki F, Lawrence PhS (eds) (1977) Chronic nonspecific respiratory disease in the City of Cracow. PZH, Warszawa
Smoking and Health. A report of the Surgeon General, DHEW Publication No 79-50066, Washington (1979)
Snedecor GW, Cochran WG (1967) Statistical methods, VI edn. University Press, Iowa
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Jedrychowski, W. Styrene and methyl methacrylate in the industrial environment as a risk factor of chronic obstructive lung disease. Int. Arch Occup Environ Heath 51, 151–157 (1982). https://doi.org/10.1007/BF00378159
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DOI: https://doi.org/10.1007/BF00378159