Article Text

other Versions

PDF
Occupational exposure to particulate air pollution and mortality due to ischemic heart disease and cerebrovascular disease
  1. Kjell Torén (kjell.toren{at}amm.gu.se)
  1. Occupational Medicine, Sweden
    1. Ingvar A Bergdahl (ingvar.bergdahl{at}envmed.umu.se)
    1. Dept of Occupational Medicine, Sweden
      1. Tohr K.F. Nilsson (tohr.nilsson{at}lvn.se)
      1. Sundsvall Hospital, Sweden
        1. Bengt Järvholm (bengt.jarvholm{at}envmed.umu.se)
        1. Occupational and environmental medicine, Sweden

          Abstract

          Objectives: A growing number of epidemiological studies are showing that ambient exposure to particulate matter air pollution is a risk factor for cardiovascular disease. Whether occupational exposure to particulate air pollution increases the risk for cardiovascular disease is not clear. The aim of the present study was to elucidate whether occupational exposure to particulate air pollution increases the risk for ischemic heart disease and cerebrovascular disease. Methods: The study population was a cohort of 176,309 occupationally exposed Swedish male construction workers and 71,778 unexposed male construction workers. The definition of exposure to inorganic dust (asbestos, man-made mineral fibers, dust from cement, concrete and quartz), wood dust, fumes (metal fumes, asphalt fumes and diesel exhaust) and gases and irritants (organic solvents and reactive chemicals) was based on a job-exposure matrix with focus on exposure in the mid-1970s. The cohort was followed from 1971 to 2002 with regard to mortality to ischemic heart disease and cerebrovascular disease. Relative risks (RR) were obtained by the person-years method and from Poisson regression models adjusting for baseline values of blood pressure, body mass index, age and smoking habits. Results: Any occupational particulate air pollution was associated with an increased risk for ischemic heart disease (RR 1.13, 95% confidence interval (CI) 1.07 – 1.19), but there was no increased risk for cerebrovascular disease (RR 0.97, 95% CI 0.88 – 1.07). There was an increased risk for ischemic heart disease and exposure to inorganic dust (RR=1.07, 95% CI 1.03-1.12) and exposure to fumes (RR=1.05, 95% CI 1.00-1.10), especially diesel exhaust (RR=1.18, 95% CI 1.13 – 1.24). There was no significantly increased risk for cerebrovascular disease and exposure to inorganic dust, fumes or wood dust. Conclusions: Occupational exposure to particulate air pollution, especially diesel exhaust, among construction workers increases the risk for ischemic heart disease.

          • air pollution
          • cardiovascular diseases
          • diesel exhaust particles
          • inorganic dust
          • occupational diseases

          Statistics from Altmetric.com

          Request permissions

          If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.