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O48-6 Expropnano project : occupational exposure assessment to nanoscale particles through measurement and work task analysis in french and canadian industries
  1. Louis Galey1,2,
  2. Sabyne Audignon- Durand1,2,3,
  3. Patrick Brochard1,2,
  4. Maximilien Debia4,
  5. Stéphane Ducamp5,
  6. Irina Guseva Canu5,
  7. Pierre Lambert6,
  8. Olivier Le Bihan7,
  9. Laurent Martinon8,
  10. Olivier Witschger9,
  11. Alain Garrigou1,2
  1. 1EPICENE, ESSAT, Centre INSERM U1219 – Bordeaux Population Health Research Centre, Bordeaux, France
  2. 2University of Bordeaux, ISPED, Bordeaux, France
  3. 3CHU De Bordeaux, Service De Médecine Du Travail Et De Pathologies Professionnelles, Bordeaux, France
  4. 4Département De Santé Environnementale Et De Santé Au Travail (DSEST), University of Montréal, Montréal, Canada
  5. 5Institut De Veille Sanitaire, Département Santé Travail, Saint Maurice, France
  6. 6Laboratoire De Chimie, Caisse d’Assurance Retraite Et De Santé Au Travail (CARSAT) – Aquitaine, Bruges, France
  7. 7Institut National De L’environnement Industriel Et Des Risques (INERIS), Verneuil en Halatte, France
  8. 8Laboratoire d’Etude Des Particules Inhalées (LEPI), Ville De Paris, Paris, France
  9. 9Institut National De Recherche Et De Sécurité (INRS), Laboratoire De Métrologie Des Aérosols, Vandoeuvre Les Nancy, France


Introduction Toxicological studies have shown potential health effects related to nanoscale particles (NP). These particles could be emitted unintentionally from usual work-processes (“ultrafine particles”) or produced intentionally for commercial purpose (“manufactured NP”) at workplace. Thus, associated exposure might concerned many workers. However, in the absence of NP strategy measurement consensus, occupational exposure is poorly monitored.

Aim In this context, the ExproPNano project aims at make operational existing NP exposure assessment recommendations, combine them with work activity analysis and test the developed strategy in French and Canadian industries involving both unintentional and manufactured NP.

Methods The first year, in 2015, was dedicated to the implementation of the project (method, team training, equipment and industries selection) with partner institutions (INRS, INERIS, LEPI, InVS, Aquitaine CARSAT, and University of Montreal – DSEST). Campaigns in different industries (aeronautics, rubber and composite, construction, mines…) will be conducted in 2016–2017 following two main steps: (1) pre-visit: prevention system analysis, process understanding, interviews and preliminary measures; (2) NP measurement and work observation: video recording synchronised with real-time measures and air sampling for physic-chemical characterisation; (3) results analysis and presentation in companies.

Expected results and conclusion Work task analysis combined with NP measurement must ensure a better understanding of the NP exposure determinants and result in recommendations of adapted prevention which may be extended to various workplaces. The tested exposure assessment method must be operational and thus easily used by all actors involved in unintentional and manufactured NP risk management. Therefore, relevant NP occupational exposure data could be produced, recording them in specific database such as Evalutil or NECID-PEROSH, it will contribute to knowledge improvement of NP exposure levels and associated health effects by public health professionals such as epidemiologists.

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