Article Text

PDF
P228 Recreational physical activity and risk of lymphoma subtypes
  1. Pierluigi Cocco1,
  2. Fahad Ahmed2,
  3. Giannina Satta1,
  4. Alessandra Argiolas1,
  5. Luigi Lecca1,
  6. Roberto Loscerbo1,
  7. Nicola Mascia1,
  8. Federico Meloni1,
  9. Sergio Pili1,
  10. Ilaria Pilia1,
  11. Tiziana Serra1,
  12. Diego Serraino1,
  13. Emanuele Angelucci3,
  14. Marcello Campagna1,
  15. Attilio Gabbas1,
  16. Marco Rais1,
  17. Maria Grazia Ennas1
  1. 1University of Cagliari, Monserrato, Italy
  2. 2Hacettepe University, Turkey
  3. 3Local Health Unit N. 8, Cagliari, Italy

Abstract

Background Physical activity is known to protect against several cancers and to improve survival and quality of life in cancer patients. Few studies have addressed the association between physical activity and risk of non Hodgkin lymphoma and its subtypes.

Methods During 1998–2004, a case-control study on the aetiology of lymphoma was conducted Sardinia, Italy as part of the European multicentre study EPILYMPH. Information on lifetime recreational physical activity was collected using a standardised questionnaire. Risk of the major lymphoma subtypes associated with ever practicing physical activity and with quartiles of hours of recreational physical activity in the lifetime was calculated with unconditional logistic regression analysis, adjusting by age, gender, education and study centre.

Results Risk of lymphoma overall and B-cell lymphoma was not associated with ever practicing recreational physical activity (OR = 0.9, 95% CI: 0.7–1.3). However, a significant protective effect was observed in the upper quartile of hours of recreational physical activity in the lifetime (OR = 0.4, 95% CI: 0.3–0.8). The inverse association was consistent across the major lymphoma subtypes, namely diffuse large B cell lymphoma, follicular lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.

Conclusions Our results suggest an inverse association between risk of the major lymphoma subtypes and prolonged recreational physical activity.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.