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P120 Comparison of correction methods of urinary biomarkers for biological monitoring of workers exposed to mercury
  1. Kyong sok Shin1,
  2. Yun Kyung Chung2,
  3. Mi-young Lee3,
  4. Chanseok Moon4
  1. 1Seegene Medical Foundation, Seoul, South Korea
  2. 2Hallym Sacred Heart Hospital, Anyang, South Korea
  3. 3Korea Occupational Safety and Health Agency, Ulsan, South Korea
  4. 4Pusan Catholic University, Pusan, South Korea

Abstract

Objectives The objective of this study was to evaluate the effect of correction methods of urinary biomarkers on airborn hazards among the workers exposed to mercury.

Methods In this research, we carried out the field survey through measurement of airborne mercury with sampling of urinary mercury. In case of mercury, the national data of urinary biological monitoring from the database of workers specialised exam and airborne mercury from the database of regular workplace measurement respectively. After enrolled of 60 samples, the subgroup analysis was conducted by the category of three variance of biological monitoring; The variance of timing of urinary sampling with airborne measurement. and the variance of difference of exposed level at airborne measurement. The statistically analysis was performed by spearman correlation and linear regression between airborne hazards and urinary biomarkers.

Results The result of fields survey is that the most strong correlation between of urinary mercury and airborne mercury was founded in the cases of urinary samples corrected by urinary creatinine.

The literature review and previous fields survey have been suggested similar results with this fields survey.

Conclusion the conclusion is that the correction by urinary creatinine would be recommended for analysis in case of urinary mercury.

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