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S10-2 Carex canada: innovations and applications
  1. Paul A Demers1,2,3,
  2. Cheryl E Peters1,3,4,
  3. Hugh W Davies1,3,5,
  4. MCalvin B Ge3,6,
  5. Amy L Hall3,5,
  6. Joanne Kim1,
  7. Jill Hardt1,
  8. Alison Palmer3,7,
  9. Anne-Marie Nicol1,3,7
  1. 1Occupational Cancer Research Centre, Toronto, Canada
  2. 2Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
  3. 3CAREX Canada, Simon Fraser University, Vancouver, Canada
  4. 4Department of Health Sciences, Carleton University, Ottawa, Canada
  5. 5School of Population and Public Health, University of British Columbia, Vancouver, Canada
  6. 6Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
  7. 7Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada


Ten years ago the CAREX Canada project was initiated with the objective of identifying how many Canadians are exposed to workplace and environmental carcinogens as well as how and where they are exposed. While the occupational component of the project was largely based on the European CAREX project, CAREX Canada sought to incorporate a number of innovations based on the Finnish job exposure matrix (FinJEM), other CAREX projects such as Costa Rica’s, and large exposure database projects that were being initiated at the time.

CAREX Canada sought to enhance the original CAREX model in two major ways. First, prevalence of exposure was assessed based on both industry (328 categories) and occupation (520 categories), using much finer groups than previous projects. This allowed for both better assessment of exposure and a finer level of reporting for targeting prevention efforts. Second, where possible, levels of exposure were estimated as three categories of low, medium, and high using cut-points based on occupational exposure limits. To facilitate this classification, the Canadian Workplace Exposure Database was created, using several hundred thousand measurements acquired from regulatory agencies. For example, we estimated that 380,000 workers are exposed to crystalline silica, 14% high (>0.025 mg/m3), 39% moderate (0.0125–0.025 mg/m3), and 47% low.

These enhancements have made CAREX Canada a much more effective tool for use in both prevention and, through creation of job exposure matrixes, epidemiologic applications. The greater granularity of the prevalence estimates and the availability of measured exposure levels for many common carcinogens have facilitated the use of this data for cancer surveillance and burden of cancer projects. Level of exposure estimation has been particularly useful, but has been limited to what can be called the “data-rich” exposures. This project has also provided a systematic means of identifying where significant data gaps exist.

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