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349 Alterations of Clinical biomarkers on Pre and Post Exercise in Obese Electronic Workers
  1. K Lee
  1. Samsung Electronics, Ltd, Yongin-city, South-Korea


Objectives The purpose of this study was to compare the pre and post-exercise clinical indicators levels such as γ-GTP, ALT, AST, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, fasting blood sugar (FBS) and HbA1C among obese electronic workers.

Methods Subjects were 26 obese workers whose average age was 31.75 year old with body mass index value over 30 kg/m2. All subjects were participated in physical exercise and diet programs during 15 weeks. Measures of clinical biomarkers such as liver function enzymes, cholesterol and diabetes indicators, blood pressure, body composition were all obtained before and after the exercise. All subjects participated in the study and gave written informed consent. Each participant completed a brief questionnaire. All data are represented as mean ± standard deviation and paired t-tests were done to compare biomarkers means between pre and post exercise.

Results The average weight showed a significant difference between before and after weight loss (95.67 ± 9.05 vs 89.36 ± 9.53 kg). Clinical liver function indicators were significantly improved after 15 weeks (ex. γ-GTP (p < 0.01), ALT (p < 0.01) and AST (p = 0.01)). Levels of total cholesterol (p < 0.01), LDL-cholesterol (p < 0.01) and triglyceride showed a significant decrease after weight loss, however HDL-cholesterol was higher levels in after exercise. And, Fasting blood sugar (p < 0.01) and HbA1C levels (p < 0.01) were significantly decreased by reduction of body weight after 15 weeks exercise.

Conclusions In conclusion, after 15 weeks combined exercise and low calorie diet programs, body composition was improved. Liver function enzymes, diabetes biomarkers and total cholesterol were significantly decreased after weight loss. These data suggest that exercise is an effective health promotion strategy for liver function, diabetes indicators and lipid profile in obese workers.

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