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Poster-discussion: Farming
AGRICOH, a newly formed consortium of agricultural cohorts
  1. ME Leon1,
  2. Laura Beane Freeman2,
  3. Jeroen Douwes3,
  4. Jane Hoppin4,
  5. Hans Kromhout5,
  6. Pierre Lebailly6,
  7. KC Nordby7,
  8. Marc Schenker8,
  9. Joachim Schüz1,
  10. SC Waring9,
  11. Michael Alavanja2,
  12. Isabelle Annesi-Maesano10,
  13. I Baldi11,
  14. Mohamed Aqiel Dalvie12,
  15. G Ferro1,
  16. B Fervers13,
  17. H Langseth14,
  18. Leslie London12,
  19. Kurt Straif1,
  20. Aaronx Blair2
  1. 1IARC, Lyon, France
  2. 2NCI, Rockville, USA
  3. 3Massey University, Wellington, New Zealand
  4. 4NIEHS, Research Triangle Park, USA
  5. 5Utrecht University, Utrecht, The Netherlands
  6. 6Université de Caen, Caen, France
  7. 7NIOH, Oslo, Norway
  8. 8University of California, Davis, USA
  9. 9Marshfield Clinic, Marshfield, USA
  10. 10INSERM & UPMC, Paris, France
  11. 11Université Bordeaux, Bordeaux, France
  12. 12University of Cape Town, Cape Town, South Africa
  13. 13Centre Léon Bérard, Lyon, France
  14. 14Cancer Registry of Norway, Oslo, Norway
  15. 15University of Iowa, Iowa City, USA
  16. 16Cancer Care Ontario, Toronto, Canada
  17. 17University of Iowa, Iowa City, USA
  18. 18University of Saskatchewan, Saskatoon, Canada
  19. 19University of Aarhus, Aarhus, Denmark
  20. 20University of Illinois, Chicago, USA
  21. 21Universidad Nacional, Heredia, Costa Rica
  22. 22Seoul National University, Seoul, Republic of Korea

Abstract

Objectives We recently formed AGRICOH, a consortium of agricultural cohort studies, offering the opportunity to investigate potential health effects of a wide range of occupational and environmental exposures coexisting in agriculture.

Methods and results AGRICOH is a consortium of 22 agricultural cohort studies initiated by US National Cancer Institute (NCI) and coordinated by International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries in 5 continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate associations between a wide range of agricultural exposures (eg, pesticides, diesel exhausts, organic dust, inorganic dust, mycotoxins, endotoxins, viruses) and a wide range of health outcomes (eg, cancer, respiratory, neurologic, auto-immune diseases, as well as reproductive and allergic disorders and injuries), with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (eg, use of infrequently applied pesticides) or relatively rare outcomes (eg, certain types of cancer, neurologic and auto-immune diseases). To facilitate future projects need for data harmonisation is required and underway. Characteristics of cohorts integrating AGRICOH, the wide range of exposures data available, data harmonisation challenges and research concepts will be illustrated.

Conclusions AGRICOH represents a great resource for conducting validation of exposure assessment and etiologic studies in association with a wide array of exposures unique to, or showing the highest likelihood of exposure, in the agricultural setting.

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