Table 3
Odds ratios and 95% confidence intervals of shift work compared with day work for increases in total cholesterol
| Variables | OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value |
| Increase by ⩾20% | Increase by ⩾25% | Increase by ⩾30% | ||||
| Job schedule type (shift/day) | 1.16 (1.07 to 1.26) | <0.001 | 1.16 (1.05 to 1.28) | 0.003 | 1.11 (0.98 to 1.25) | 0.089 |
| Baseline total cholesterol (mg/dl) | 0.67 (0.65 to 0.69) | <0.001 | 0.63 (0.62 to 0.65) | <0.001 | 0.61 (0.59 to 0.64) | <0.001 |
| Age | 1.00 (0.99 to 1.00) | 0.544 | 1.00 (0.99 to 1.01) | 0.870 | 1.00 (0.99 to 1.00) | 0.602 |
| Body mass index (kg/m2) | 1.02 (1.00 to 1.03) | 0.054 | 1.03 (1.01 to 1.05) | 0.001 | 1.05 (1.03 to 1.08) | <0.001 |
| Creatinine (mg/dl) | 0.99 (0.97 to 1.01) | 0.314 | 0.98 (0.95 to 1.01) | 0.134 | 0.98 (0.94 to 1.01) | 0.159 |
| Glycated haemoglobin A1c (%) | 1.04 (1.00 to 1.08) | 0.079 | 1.07 (1.02 to 1.12) | 0.004 | 1.09 (1.03 to 1.15) | 0.002 |
| Aspartate aminotransferase (IU/l) | 1.01 (0.99 to 1.02) | 0.305 | 1.01 (1.00 to 1.03) | 0.101 | 1.02 (1.00 to 1.04) | 0.075 |
| γ-Glutamyl transpeptidase (IU/l) | 1.02 (1.01 to 1.03) | <0.001 | 1.02 (1.01 to 1.03) | <0.001 | 1.02 (1.01 to 1.03) | <0.001 |
| Uric acid (mg/dl) | 0.99 (0.97 to 1.01) | 0.252 | 1.00 (0.98 to 1.02) | 0.750 | 1.01 (0.98 to 1.03) | 0.668 |
| Drinking habit (everyday/not everyday) | 0.87 (0.79 to 0.96) | 0.003 | 0.86 (0.77 to 0.96) | 0.006 | 0.91 (0.79 to 1.04) | 0.158 |
| Smoking habit (smokers/non-smokers) | 1.02 (0.93 to 1.11) | 0.704 | 1.01 (0.91 to 1.12) | 0.846 | 1.04 (0.92 to 1.18) | 0.545 |
| Regular exercise (absence/presence) | 0.97 (0.89 to 1.06) | 0.503 | 0.90 (0.81 to 0.99) | 0.035 | 0.89 (0.79 to 1.01) | 0.070 |
| Increase by ⩾35% | Increase by ⩾40% | Increase by ⩾45% | ||||
| Job schedule type (shift/day) | 1.23 (1.05 to 1.43) | 0.009 | 1.30 (1.07 to 1.58) | 0.007 | 1.28 (1.01 to 1.63) | 0.045 |
| Baseline total cholesterol (mg/dl) | 0.57 (0.55 to 0.60) | <0.001 | 0.55 (0.52 to 0.58) | <0.001 | 0.54 (0.50 to 0.57) | <0.001 |
| Age | 1.00 (0.99 to 1.01) | 0.490 | 1.00 (0.99 to 1.01) | 0.869 | 0.99 (0.98 to 1.01) | 0.249 |
| Body mass index (kg/m2) | 1.07 (1.04 to 1.10) | <0.001 | 1.10 (1.06 to 1.13) | <0.001 | 1.10 (1.05 to 1.15) | <0.001 |
| Creatinine (mg/dl) | 0.97 (0.93 to 1.02) | 0.197 | 0.96 (0.91 to 1.01) | 0.137 | 0.96 (0.89 to 1.03) | 0.252 |
| Glycated haemoglobin A1c (%) | 1.12 (1.05 to 1.20) | 0.001 | 1.16 (1.07 to 1.26) | 0.001 | 1.15 (1.03 to 1.28) | 0.013 |
| Aspartate aminotransferase (IU/l) | 1.02 (0.99 to 1.04) | 0.136 | 1.03 (1.00 to 1.06) | 0.037 | 1.03 (0.99 to 1.06) | 0.161 |
| γ-Glutamyl transpeptidase (IU/l) | 1.03 (1.02 to 1.05) | <0.001 | 1.03 (1.01 to 1.05) | <0.001 | 1.03 (1.01 to 1.05) | 0.007 |
| Uric acid (mg/dl) | 1.01 (0.97 to 1.04) | 0.682 | 1.02 (0.97 to 1.06) | 0.442 | 1.05 (0.99 to 1.11) | 0.087 |
| Drinking habit (everyday/not everyday) | 0.89 (0.75 to 1.06) | 0.182 | 0.96 (0.78 to 1.20) | 0.746 | 1.15 (0.87 to 1.51) | 0.328 |
| Smoking habit (smokers/non-smokers) | 1.06 (0.90 to 1.24) | 0.506 | 1.02 (0.83 to 1.26) | 0.836 | 0.96 (0.74 to 1.24) | 0.762 |
| Regular exercise (absence/presence) | 0.99 (0.85 to 1.16) | 0.940 | 0.90 (0.74 to 1.10) | 0.306 | 1.00 (0.78 to 1.27) | 0.983 |
-
The data for total cholesterol, creatinine, glycated haemoglobin A1c, aspartate aminotransferase, γ-glutamyl transpeptidase and uric acid were logarithmically transformed using a base of 1.1. All covariates were included in the model.
-
OR, odds ratio, estimated as the ratio of the former to the latter for job schedule type, drinking habits, smoking habits.
