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Occup Environ Med 66:143-149 doi:10.1136/oem.2008.041921
  • Original article
    • 1507

Maternal levels of dichlorodiphenyl-dichloroethylene (DDE) may increase weight and body mass index in adult female offspring

Table 4 Regression coefficients for predictors of adult female offspring height, weight and body mass index (repeated measurements in 2001/02 and 2006/07) derived from repeated measurement models adjusting for having the same mother (within-family effect)†
Height (cm) Weight (kg) BMI (kg/m2)
Number of mothers = 101, number of participants = 169, number of observations = 267 Number of mothers = 101, number of participants = 169, number of observations = 267 Number of mothers = 101, number of participants = 169, number of observations = 267
Estimate Standard error Estimate Standard error Estimate Standard error
Maternal DDE (μg/l)
    1.503–2.9‡ 1.17 0.82 5.93* 1.79 1.65* 0.33
    >2.9 1.29 1.05 9.22* 3.06 2.88* 0.92
Maternal PCB (μg/l)
    0.05–1.94§ −0.10 0.88 0.93 2.35 −0.39 0.74
    >1.94 −1.51 1.50 2.29 3.43 1.28 1.18
Maternal height (cm) 0.07 0.26
Maternal BMI (kg/m2) 1.59* 0.73 0.56* 0.25
Breastfed as a child (%) −0.30 0.54 2.73 2.44 1.21 0.95
Birth weight of the offspring¶
    <2500 g −0.01 0.01 −5.47* 0.98 −2.07* 0.37
    >4000 g 4.89 2.47 5.30 6.30 0.29 1.78
Height of the offspring (cm) 0.055 0.34
Age of the adult female offspring (years) 1.02* 0.18 0.39* 0.07
Number of offspring’s pregnancies**
    1 2.44 2.74 1.13 0.93
    2 0.31 3.28 0.14 1.20
    3 or more 0.40 3.26 0.29 1.12
  • *p⩽0.05.

  • †Each outcome is adjusted for all other variables in the model; ‡maternal DDE at birth of the offspring of 0 to <1.5 μg/l is the reference; §maternal PCB at birth of the offspring of <0.05 μg/l is the reference; ¶birth weight of 2500–4000 g is the reference; **female offspring without pregnancies serve as the reference.

  • BMI, body mass index; DDE, dichlorodiphenyl-dichloroethylene; PCB, polychlorinated biphenyl.

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