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Occup Environ Med 2008;65:i
  • Work in Brief

Work in Brief

  1. Keith Palmer, Editor

      Organochlorine compounds and thyroid function

      Organochlorine compounds (OCs), such as polychlorinated biphenyls (PCBs) and dioxins, have been linked with hypothyroidism both in animal and human studies but the relationship is not clearly established. OCs can be found in human milk, blood and adipose tissue and their potential effects in young children and adolescents are of special concern given the role of thyroid hormones in myelination and neurodevelopment. Álvarez-Pedrerol and colleagues have evaluated the relationship between certain OCs (p,p’-DDT, ß-HCH, PCB congeners) and concentrations of free T4, total T3 and thyrotropin in the blood of 259 preschool children …

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