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Mesothelin in effusions marks out malignancy

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An ELISA assay for mesothelin should make it easier and faster to identify malignant mesothelioma from patients’ pleural effusions, especially in centres with limited expertise in cytopathological diagnosis.

Researchers have found that the test, which has already been used to detect soluble mesothelin–a marker for the cancer—in serum, can be successfully applied to effusions.

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