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Occup Environ Med 64:701-707 doi:10.1136/oem.2006.031146
  • Original article

Limits of longitudinal decline for the interpretation of annual changes in FEV1 in individuals

Table 3 The relative pair-wise within-person variation s̄r, and the relative limit of longitudinal decline LLDr for individuals with asthma and with COPD by quartiles of bronchial hypereactivity (BHR)
Program Condition %ΔFEV1 (n) s̄r (%) LLDr (%) 95th percentile %ΔFEV1
P1 Asthma 83 5.2 12.8 11.6
P4 COPD & BHRq1† 7112 7.3 17.9 18.9
P4 COPD & BHRq2 6575 5.8 14.6 15.3
P4 COPD & BHRq3 8830 4.9 12.3 12.2
P4 COPD & BHRq4 2925 4.3 10.9 10.5

  • †BHRq1-q4 represent quartiles of BHR; q1 is highest and q4 is lowest degree of BHR.

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