Monitoring of fluoro-edenite fibre pollution through the study of sheep lymph nodes as a model of a biological indicator
- V Rapisarda1,
- G Rapisarda2,
- G D Vico2,
- L Gobbi3,
- C Loreto4,
- M Valentino5
- 1Department of Social and Environmental Medicine, Occupational Medicine Section, University of Messina, Italy
- 2Department of Veterinary Public Health, Pathology Section, University of Messina, Italy
- 3Department of Material Physics and Engineering, University of Ancona, Italy
- 4Department of Anatomy, Diagnostic Pathology, Forensic Medicine, Hygiene and Public Health, University of Catania, Italy
- 5Department of Molecular Pathology, Occupational Medicine Section, Polytechnic University of Marche, Ancona, Italy
- Correspondence to: Prof. M Valentino Department of Molecular Pathology, Occupational Medicine Section, Polytechnic University of Marche, Ancona, Via Tronto 10/a 60020 Torrette, Ancona, Italy; m.valentinounivpm.it
A significantly increased standardised rate of mortality from pleural mesothelioma, comparable to that reported in asbestos exposed cohorts, has been recorded in Biancavilla (SW slope of Mt Etna, Sicily)1,2 and attributed to exposure to fluoro-edenite, a fibrous amphibole found in the inert material extracted from a nearby stone quarry.1
It is well known that sheep lung is anatomically and physiologically comparable to human lung,3 and lymph nodes are …









