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Occup Environ Med 62:598-606 doi:10.1136/oem.2004.017640
  • Original article

Asthma, chronic bronchitis, and exposure to irritant agents in occupational domestic cleaning: a nested case-control study

Table 4

 Multivariate associations (adjusted odds ratios and 95% confidence intervals) between asthma/chronic bronchitis symptoms, and risk factors

Controls (n = 152*) All cases (n = 40) OR (95% CI) Asthma (n = 24) OR (95% CI) Chronic bronchitis without asthma (n = 16) OR (95% CI)
Multiple logistic regression analyses adjusted for all listed variables and age tertile.
*Three controls had missing values for one or more of the exposure variables and were not included in this multivariate model.
Bleach (both undiluted and diluted)
    <364 times/year 56 8 1.0 3 1.0 5 1.0
    364–640 times/year 53 11 3.3 (0.9 to 11) 9 10 (1.7 to 60) 2 0.9 (0.1 to 6.5)
    ⩾640 times/year 43 21 4.9 (1.5 to 15) 12 12 (2.3 to 67) 9 2.6 (0.6 to 12)
Use of liquid multi-use cleaning products
    <266 times/year 50 20 1.0 13 1.0 7 1.0
    266–480 times/year 51 12 0.3 (0.1 to 0.8) 6 0.2 (0.0 to 0.7) 6 0.3 (0.1 to 1.6)
    ⩾480 times/year 51 8 0.2 (0.1 to 0.6) 5 0.1 (0.0 to 0.5) 3 0.2 (0.0 to 1.3)
Washing dishes
    <376 times/year 64 10 1.0 8 1.0 2 1.0
    376–520 times/year 37 12 3.2 (1.0 to 10) 6 2.0 (0.5 to 8.9) 6 7.5 (1.0 to 53)
    ⩾520 times/year 51 18 3.1 (1.1 to 8.9) 10 3.8 (1.0 to 14) 8 6.5 (0.9 to 47)
Inhalation of an important quantity of vapours, gas, or fumes related to cleaning agents
    Never 73 9 1.0 5 1.0 4 1.0
    Ever 79 31 2.3 (0.9 to 6.1) 19 3.8 (1.0 to 14) 12 0.9 (0.2 to 4.3)
Employment in non-domestic cleaning
    Never 101 9 1.0 5 1.0 4 1.0
    Ever 51 31 8.5 (3.2 to 23) 19 12 (3.2 to 46) 12 7.9 (1.6 to 39)
Smoking
    Never 127 25 1.0 19 1.0 6 1.0
    Currently 15 11 4.1 (1.1 to 15) 2 0.5 (0.1 to 3.9) 9 22 (3.6 to 137)
    Formerly 10 4 5.3 (1.1 to 25) 3 5.5 (0.9 to 33) 1 8.9 (0.5 to 173)

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