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Occup Environ Med 62:330-336 doi:10.1136/oem.2004.017129
  • Original article

The use of biomarkers of exposure of N,N-dimethylformamide in health risk assessment and occupational hygiene in the polyacrylic fibre industry

Table 2

 Median concentrations of N-methylformamide (NMF) and N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) in urine, and N-methylcarbamoylated haemoglobin (NMHb) in blood of workers exposed to N,N-dimethylformamide (DMF) in dependence on different job tasks

No. Job description NMF (mg/l) NMF (mg/g) AMCC (mg/l) AMCC (mg/g) NMHb (nmol/g)
Volume and creatinine related concentrations are given for NMF and AMCC. n, number of workers.
Exposure group 1 1 Fibre crimping (n = 11/12) 8.7 7.4 5.5 6.4 49.0
2 Person in charge (n = 1) 4.7 6.5 6.2 8.6 148.8
3 Spinning solution (n = 1) 8.0 3.1 38.6 14.9 169.6
Exposure group 2 1 Spinning machine (n = 14) 18.6 11.3 17.7 14.6 122.8
Exposure group 3 1 Precipitation bath (n = 1) 9.6 5.1 29.1 15.5 135.6
2 Washing machine (n = 1) 27.6 12.0 116.5 50.6 205.7
3 Colouring (n = 2) 21.4 18.9 17.0 12.3 143.0
4 Fibre tows (n = 3) 32.2 13.7 11.3 13.7 191.4

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