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Occup Environ Med 62:124-127 doi:10.1136/oem.2004.013797
  • Short report

Haloacetic acids in drinking water and risk for stillbirth

Table 2

 Relative risks (RR) and 95% confidence intervals (95% CI) for by-product total exposure measures and risk of stillbirth

Exposure Cases n = 112 Controls n = 398 Adjusted RR (95% CI)* THM adjusted RR (95% CI)†
*Adjusted for maternal age, province, income, occupation, and smoking during pregnancy.
†Adjusted for maternal age, province, income, occupation, smoking during pregnancy, and total THM exposure.
Total HAA
    No exposure 27 24% 116 29% 1.00 1.00
    Tertile 1 (lowest) 18 16% 94 24% 0.93 (0.46 to 1.89) 0.85 (0.41 to 1.74)
    Tertile 2 40 36% 94 24% 2.35 (1.27 to 4.34) 1.91 (0.97 to 3.76)
    Tertile 3 27 24% 94 24% 1.35 (0.70 to 2.63) 0.94 (0.41 to 2.18)
DCAA
    No exposure 30 27% 127 32% 1.00 1.00
    Tertile 1 (lowest) 29 26% 91 23% 1.54 (0.82 to 2.88) 1.28 (0.67 to 2.46)
    Tertile 2 30 27% 90 23% 1.99 (1.05 to 3.76) 1.45 (0.72 to 2.91)
    Tertile 3 23 20% 90 23% 1.17 (0.60 to 2.31) 0.66 (0.28 to 1.56)
TCAA
    No exposure 32 29% 127 32% 1.00 1.00
    Tertile 1 (lowest) 30 27% 91 23% 1.54 (0.83 to 2.87) 1.31 (0.69 to 2.51)
    Tertile 2 19 17% 90 23% 1.13 (0.57 to 2.24) 0.87 (0.41 to 1.84)
    Tertile 3 31 28% 90 23% 1.52 (0.82 to 2.83) 1.02 (0.48 to 2.20)
Brominated HAA
    No exposure 37 33% 151 38% 1.00 1.00
    Tertile 1 (lowest) 19 17% 83 21% 1.15 (0.59 to 2.23) 1.03 (0.52 to 2.03)
    Tertile 2 27 24% 82 21% 1.43 (0.77 to 2.66) 1.24 (0.65 to 2.37)
    Tertile 3 29 26% 82 21% 1.60 (0.88 to 2.89) 1.29 (0.67 to 2.49)

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