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Occup Environ Med 62:885-889 doi:10.1136/oem.2005.020834
  • Original article

The effect of asbestosis on lung cancer risk beyond the dose related effect of asbestos alone

Table 2

 Relative risk of lung cancer from exposure to asbestos (fibres/ml-year) and asbestosis

Unadjusted HR (95% CI) p value Adjusted* HR (95% CI) p value
*Adjusted for all covariates.
Non-smoker 1.00 1.00
Past smoker 18.1 (2.48 to 132.5) 0.004 9.53 (1.29 to 70.6) 0.027
Current smoker 30.1 (4.06 to 223.7) 0.001 26.5 (3.54 to 198.5) 0.001
Asbestosis 4.71 (2.72 to 8.14) 0.007 1.94 (1.09 to 3.46) 0.025
Age at start of study 1.08 (1.05 to 1.11) 0.000 1.07 (1.04 to 1.11) 0.000
Male 4.09 (1.63 to 10.3) 0.003 1.24 (0.41 to 3.75) 0.701
Ex-resident 0.14 (0.06 to 0.35) 0.000 0.49 (0.16 to 1.48) 0.206
Cumulative exposure
(log f/ml-y) 1.44 (1.22 to 1.71) 0.000 1.21 (1.02 to 1.42) 0.026

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