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Occup Environ Med 61:680-685 doi:10.1136/oem.2003.010934
  • Original article

Mortality and cancer incidence among alachlor manufacturing workers 1968–99

Table 4

 Standardised incidence ratios* (SIRs) for various cancers for employees with potential alachlor exposure (workplace or drinking water)

Type of cancer Any alachlor exposure High alachlor exposure 5+ years high exposure 15+ years since first exposure
O/E† SIR 95% CI O/E† SIR 95% CI O/E† SIR 95% CI
*SIRs and 95% CIs were not calculated unless observed or expected cases exceeded 1.
†Observed number of cases/expected number of cases.
All cancers 36/28.3 127 89 to 176 29/23.4 123 82 to 177 8/7.1 113 49 to 224
Buccal cavity 2/1.4 144 17 to 520 2/1.2 163 20 to 590 0/0.5
Digestive 8/5.6 142 61 to 279 6/4.9 122 45 to 265 2/1.9 108 13 to 389
    Colon 4/2.4 169 46 to 434 4/2.1 194 53 to 497 2/0.8 256 31 to 925
    Rectum 2/1.3 160 19 to 580 0/1.1 0 0 to 224 0/0.4
    Liver, gall bladder 1/0.4 1/0.3 0/0.1
    Pancreas 1/0.6 1/0.6 0/0.2
Lung 2/4.5 45 5 to 162 2/4.0 50 6 to 181 1/1.7 59 2 to 327
Melanoma 6/2.2 278 102 to 606 4/1.8 229 62 to 587 0/0.4
Breast 2/2.8 71 9 to 255 2/2.0 101 12 to 363 0/0.3
Female genital 2/1.5 136 17 to 492 1/1.0 0/0.2
Prostate 4/3.5 115 31 to 295 4/3.2 125 34 to 319 2/1.7 120 15 to 434
Testis 3/1.3 235 49 to 686 1/1.0 0/0.1
Kidney 1/1.1 94 2 to 526 1/0.9 1/0.4
Non-Hodgkin’s lymphoma 3/1.7 173 36 to 504 3/1.5 207 43 to 604 1/0.5
Hodgkin’s disease 1/0.7 1/0.5 0/0.1
Leukaemia 2/1.1 176 21 to 636 2/1.0 206 25 to 744 0/0.3
    Chronic myeloid leukaemia 2/0.2 955 116 to 3448 2/0.17 1165 141 to 4210 0/0.04

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