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Occup Environ Med 61:577-585 doi:10.1136/oem.2003.012443
  • Original article

Mortality of employees of the United Kingdom Atomic Energy Authority, 1946–97

Table 5

 Mortality of workers monitored for internal contamination compared with other radiation workers and trends of mortality in those workers with cumulative external unlagged radiation dose; rate ratios and trend tests are adjusted for age, sex, calendar year, and social class

ICD code, 9th revision Disease RR 95% CI Dose trend
Observed/expected deaths χ12(direction of trend) p
<10 mSv 10–<20 mSv 20–<50 mSv 50–<100 mSv 100+ mSv
140–208 All malignant neoplasms 1.01 (0.90–1.13) 59/67.9 58/58.3 150/136.5 105/109.8 167/166.5 0.0 (+) 1.00
140–149 Buccal cavity and pharynx 0.67 (0.24–1.86) 0/0.8 1/0.7 0/1.7 2/0.9 3/1.9 1.0 (+) 0.32
150 Oesophagus 0.65 (0.36–1.18) 0/1.9 3/2.3 5/3.9 4/4.1 6/6.0 0.0 (+) 0.92
151 Stomach 1.01 (0.67–1.51) 6/4.8 5/4.4 12/10.7 5/8.1 13/13.0 0.1 (−) 0.82
153 Large intestine 1.02 (0.69–1.50) 3/5.0 6/5.8 14/10.3 10/9.3 10/12.5 0.3 (−) 0.58
154 Rectum 1.04 (0.60–1.82) 2/2.4 2/1.8 10/6.6 3/4.8 5/6.4 0.4 (−) 0.52
155–156 Liver and gall bladder 1.14 (0.47–2.77) 3/1.9 1/1.3 4/2.2 1/1.6 0/2.0 2.2 (−) 0.14
157 Pancreas 0.70 (0.38–1.32) 1/1.6 3/1.7 6/3.9 3/3.0 2/4.8 1.4 (−) 0.23
161 Larynx 1.17 (0.14–6.35) 0/0.6 0/0.3 1/0.8 1/0.9 2/1.4 0.3 (+) 0.59
162 Bronchus and lung 1.04 (0.85–1.27) 24/20.9 15/16.9 45/41.3 36/34.0 51/57.8 0.7 (−) 0.41
163 Pleura 1.80 (0.43–∞) 0/0.4 0/0.7 2/1.1 3/1.5 0/1.3 0.5 (−) 0.46
172 Malignant melanoma 1.50 (0.56–4.06) 0/0.8 1/1.2 1/1.7 1/1.5 4/1.7 2.9 (+) 0.09
174 Breast 0.73 (0.00–2.56) 1/1 0/0.5 0/0.2 0/0 1/0.4 1.9 (+) 0.17
179–182 All uterus 6.59 (1.40–43.60) 2/2.54 1/0.4 0/0.9 1/0.05 0/0.12 0.0 (+) 0.86
180 Cervix 1.11 (0.00 –∞) 0/1 0/0 0/0 1/0 0/0 365.0 (+) 0.00
179, 182 Endometrium 12.96 (1.65–∞) 2/1.5 1/0.4 0/0.9 0/0.05 0/0.12 0.4 (−) 0.51
183 Ovary
185 Prostate, all years 1.39 (0.95–2.04) 3/5.0 2/5.1 14/14.0 10/12.1 20/12.8 3.60 (+) 0.06
Prostate, 1946–79 1.36 (0.90–2.08) 0/1.09 0/1.29 2/3.6 1/1.9 8/3.1 7.0 (+) 0.01
Prostate, 1980–97 0.75 (0.61–0.93) 3/3.9 2/3.8 12/10.4 9/10.2 12/9.7 0.5 (+) 0.49
186 Testis 1.11 (0.25–5.19) 0/0.6 1/0.6 1/1.1 0/0.5 1/0.3 1.5 (+) 0.23
188–189 Urinary 1.08 (0.70–1.65) 2/4.4 4/3.5 10/8.8 6/6.7 14/12. 7 0.2 (+) 0.68
189.0 Kidney 0.99 (0.49–1.97) 1/1.2 4/1.3 5/3.7 2/3.0 1/3.9 2.4 (−) 0.12
191–192 Brain and other central nervous system 0.74 (0.34–1.58) 5/2.2 1/1.2 1/2.7 1/2.4 3/2.5 0.0 (+) 1.00
193 Thyroid 0.50 (0.00–∞) 0/0.05 0/0.07 0/0.3 0/0.2 1/0.4 0.9 (+) 0.33
195–199 Ill defined and secondary 1.53 (1.01–2.32) 4/5.4 4/4.8 17/12.1 6/8.4 13/13.4 0.0 (−) 0.89
200–208 All lymphatic and haematopoietic 0.74 (0.50–1.10) 3/5.0 7/4.76 4/9.9 11/8.5 16/12.9 0.9 (+) 0.34
200,202 Non-Hodgkin’s lymphoma 0.68 (0.36–1.27) 1/1.7 4/1.8 0/3.9 4/2.5 6/5.0 0.2 (+) 0.62
201 Hodgkin’s disease 0.54 (0.00–4.64) 0/0.06 0/0.03 0/0.11 1/0.11 0/0.7 0.4 (−) 0.54
203 Multiple myeloma 1.20 (0.37–3.69) 1/0.9 1/0.5 1/1.4 3/2.4 2/2.8 0.2 (−) 0.70
204–208 Leukaemia 0.71 (0.39–1.28) 1/2.3 2/2.4 3/4.5 3/3.5 8/4.5 2.6 (+) 0.11
204–208 excl. 204.1 Leukaemia excl. CLL 0.88 (0.45–1.72) 1/2.0 2/2.1 3/3.9 1/2.5 7/3.4 3.0 (+) 0.08
410–414 Ischaemic heart disease 0.94 (0.85–1.05) 80/70.4. 53/63.1 154/153.6 133/125.3 216/223.7 0.2 (−) 0.67
460–519 Respiratory disease 0.75 (0.60–0.92) 15/15.6 12/14.0 44/34.1 18/27.7 43/40.7 0.0 (+) 0.92
800–999 Accidents, suicides, and violence 0.86 (0.67–1.12) 27/21.1 11/12.5 20/19.1 11/13.7 17/19.6 0.7 (+) 0.41
000–999 All causes 0.94 (0.88–0.99) 232/228 180/193 466/444 355/358 571/580 0.1 (−) 0.72

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