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Occup Environ Med 2004;61:548-550 doi:10.1136/oem.2003.008805
  • Short report

Enhanced oxidative stress in workers with a standing occupation

  1. R Flore1,
  2. L Gerardino1,
  3. A Santoliquido1,
  4. R Pola3,
  5. A Flex1,
  6. C Di Campli1,
  7. P Pola1,
  8. P Tondi2
  1. 1Department of Medicine, A. Gemelli University Hospital, Catholic University of the Sacred Heart, Rome, Italy
  2. 2Division of Vascular Medicine, A. Gemelli University Hospital, Catholic University of the Sacred Heart, Rome, Italy
  3. 3Laboratory of Vascular Biology and Genetics, A. Gemelli University Hospital, Catholic University of the Sacred Heart, Rome, Italy
  1. Correspondence to:
 Dr R Flore
 Department of Medicine, Catholic University of the Sacred Heart, A. Gemelli University Hospital, Largo A. Gemelli, 8-00165 Rome, Italy; angiologiarm.unicatt.it
  • Accepted 4 August 2003

Abstract

Background: Several epidemiological studies have shown a statistically significant association between standing work and chronic venous insufficiency of lower limbs. This condition has been associated with an enhanced oxidative stress that, according to the literature, could represent a risk factor for cardiovascular and other systemic diseases.

Aims and Methods: To evaluate venous pressure of the lower limbs and reactive oxygen species (ROS) before and after work in 62 workers with a standing occupation (surgery room nurses) and 65 outpatient department nurses who can walk during their working time.

Results: After work, a statistically significant increase of venous pressure of the lower limbs levels was observed in both the study group and controls. Standing workers showed significantly higher mean levels of ROS after work.

Footnotes

  • The research was funded by an unrestricted grant from ISPESL (National Institute for Occupational Safety and Prevention, Italy)

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