Table 3
Cox proportional hazards regression results (rate ratios) by cancer site, MWF type, and time window
| Cancer site | Total time | Recent 10 years* | 10–20 years | 20+ years | ||||
|---|---|---|---|---|---|---|---|---|
| RR† | 95% CI | RR | 95% CI | RR | 95% CI | RR | 95% CI | |
| Rate ratios presented for 5 mg/m3-years of cumulative exposure. | ||||||||
| *Exposure windows prior to risk age. Windows are adjusted for each other in the models. | ||||||||
| †Rate ratios compare 5 mg/m3-years of exposure to the unexposed. | ||||||||
| ‡Insufficient data. | ||||||||
| §SCC, squamous cell carcinoma. | ||||||||
| ¶Grinding, without regard to MWF type. | ||||||||
| **ADC, adenocarcinoma. | ||||||||
| Larynx SCC (n = 78) | ||||||||
| Soluble | 0.97 | 0.91 to 1.04 | 1.22 | 0.56 to 2.66 | 0.72 | 0.46 to 1.14 | 1.00 | 0.93 to 1.07 |
| Straight | 1.07 | 1.01 to 1.12 | 0.12 | 0.01 to 1.89 | 1.42 | 0.97 to 2.07 | 1.06 | 0.99 to 1.13 |
| Synthetic | 1.03 | 0.76 to 1.39 | –‡ | –‡ | 1.25 | 0.30 to 5.22 | 1.09 | 0.75 to 1.56 |
| Stomach carcinoma (n = 77) | ||||||||
| Soluble | 1.00 | 0.95 to 1.05 | 1.29 | 0.63 to 2.67 | 0.96 | 0.68 to 1.33 | 1.00 | 0.95 to 1.06 |
| Straight | 0.96 | 0.84 to 1.08 | 1.25 | 0.19 to 8.29 | 0.94 | 0.42 to 2.08 | 0.95 | 0.82 to 1.11 |
| Synthetic | 0.68 | 0.32 to 1.43 | 1.47 | 0.08 to 27.19 | 0.32 | 0.01 to 7.89 | 0.72 | 0.29 to 1.80 |
| Oesophageal SCC§ (n = 37) | ||||||||
| Soluble | 0.94 | 0.84 to 1.04 | 1.42 | 0.65 to 3.11 | 0.92 | 0.54 to 1.56 | 0.92 | 0.81 to 1.06 |
| Straight | 0.93 | 0.75 to 1.15 | 2.99 | 0.25 to 35.47 | 0.31 | 0.03 to 3.01 | 0.99 | 0.79 to 1.23 |
| Synthetic | 0.99 | 0.60 to 1.63 | –‡ | –‡ | –‡ | –‡ | 1.39 | 0.85 to 2.28 |
| Grinding¶ | 0.96 | 0.86 to 1.07 | 2.15 | 0.70 to 6.58 | 0.79 | 0.36 to 1.74 | 0.95 | 0.82 to 1.09 |
| Oesophageal and cardia junction ADC** (n = 36) | ||||||||
| Soluble | 1.01 | 0.94 to 1.09 | 0.60 | 0.12 to 3.15 | 0.92 | 0.53 to 1.61 | 1.03 | 0.96 to 1.11 |
| Straight | 1.01 | 0.88 to 1.15 | 2.49 | 0.24 to 25.32 | 0.34 | 0.05 to 2.40 | 1.06 | 0.93 to 1.21 |
| Synthetic | –‡ | –‡ | –‡ | –‡ | 1.29 | 0.11 to 14.74 | 0.93 | 0.42 to 2.07 |
