Table 4
Exposure to psychosocial factors according to the FINJEM and dementia (total dementia, possible Alzheimer’s disease, and possible vascular dementia)
| Variable | R | % | All cases with dementia (n = 195) | Cases with possible AD (n = 108) | Cases with possible VD (n = 59) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C | Adj. OR† | 95% CI | C | % | Adj. OR† | 95% CI | C | % | Adj. OR† | 95% CI | ||||
| C, cases; R, control group subjects; AD, Alzheimer’s disease; VD, vascular disease. | ||||||||||||||
| In the assessment of the time weighted mean score of psychosocial exposures, probands with <10 years estimable worktime were excluded from analysis. | ||||||||||||||
| *To calculate tests for trend, the exposure scores were included as continuous variables in the logistic regression model. | ||||||||||||||
| †Adjusted for age, region, sex, dementia in parents, education, smoking (pack-years), and psychosocial network at age 30. | ||||||||||||||
| Challenge at work (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽3.5 | 52 | 22.7 | 64 | 32.8 | 1.0 | – | 38 | 35.2 | 1.0 | – | 21 | 35.6 | 1.0 | – |
| >3.5, <4.5 | 142 | 62.0 | 98 | 50.3 | 0.5 | 0.3 to 0.9 | 49 | 45.4 | 0.3 | 0.2 to 0.7 | 32 | 54.2 | 0.5 | 0.2 to 1.1 |
| ⩾4.5 | 2 | 0.9 | – | – | – | – | – | – | – | – | – | – | – | – |
| p for trend* | p = 0.01 | p = 0.007 | p = 0.04 | |||||||||||
| Social climate at work (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽3.5 | 106 | 43.6 | 81 | 41.5 | 1.0 | – | 48 | 44.4 | 1.0 | – | 25 | 42.4 | 1.0 | – |
| >3.5, <4.5 | 90 | 39.3 | 81 | 41.5 | 1.3 | 0.8 to 2.2 | 39 | 36.1 | 1.2 | 0.6 to 2.3 | 28 | 47.5 | 1.2 | 0.6 to 2.6 |
| ⩾4.5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| p for trend* | p = 0.42 | p = 0.50 | p = 0.96 | |||||||||||
| Control possibilities at work (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽3.5 | 28 | 12.2 | 32 | 16.4 | 1.0 | – | 16 | 14.8 | 1.0 | – | 12 | 20.3 | 1.0 | – |
| >3.5, <4.5 | 168 | 73.4 | 130 | 66.7 | 0.5 | 0.3 to 1.1 | 71 | 65.7 | 0.6 | 0.2 to 1.4 | 41 | 69.5 | 0.4 | 0.2 to 1.2 |
| ⩾4.5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| p for trend* | p = 0.02 | p = 0.10 | p = 0.03 | |||||||||||
| Work load (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽2.0 | 30 | 13.1 | 22 | 11.3 | 1.0 | – | 14 | 13.0 | 1.0 | – | 6 | 10.2 | 1.0 | – |
| >2.0, <3.0 | 95 | 41.5 | 62 | 31.8 | 1.0 | 0.4 to 2.3 | 28 | 25.9 | 0.5 | 0.2 to 1.5 | 29 | 49.2 | 2.2 | 0.6 to 8.6 |
| ⩾3.0 | 71 | 31.0 | 78 | 40.0 | 2.0 | 0.9 to 4.6 | 45 | 41.7 | 2.1 | 0.8 to 5.6 | 18 | 30.5 | 1.7 | 0.4 to 6.3 |
| p for trend* | p = 0.24 | p = 0.19 | p = 0.61 | |||||||||||
| Perceived risks for error at work (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽2.0 | 132 | 57.6 | 105 | 53.8 | 1.0 | – | 59 | 54.6 | 1.0 | – | 30 | 50.8 | 1.0 | – |
| >2.0, <3.0 | 45 | 19.7 | 39 | 20.0 | 1.1 | 0.6 to 2.3 | 20 | 18.5 | 1.4 | 0.6 to 3.5 | 16 | 27.1 | 1.5 | 0.6 to 4.1 |
| ⩾3.0 | 19 | 8.3 | 18 | 9.2 | 2.1 | 0.8 to 5.4 | 8 | 7.4 | 2.2 | 0.5 to 8.7 | 7 | 11.9 | 2.1 | 0.6 to 7.2 |
| p for trend* | p = 0.001 | p = 0.009 | p = 0.004 | |||||||||||
| Social demands at work (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽3.5 | 131 | 57.2 | 114 | 58.5 | 1.0 | – | 59 | 54.6 | 1.0 | – | 43 | 72.9 | 1.0 | – |
| >3.5, <4.5 | 56 | 24.5 | 45 | 23.1 | 1.0 | 0.6 to 1.9 | 25 | 23.1 | 1.4 | 0.7 to 3.1 | 10 | 16.9 | 0.4 | 0.1–1.0 |
| ⩾4.5 | 9 | 3.9 | 3 | 1.5 | 0.2 | 0.04 to 1.3 | 3 | 2.8 | 0.5 | 0.1 to 2.7 | – | – | – | – |
| p for trend* | p = 0.05 | P = 0.19 | p = 0.01 | |||||||||||
| Supervisor support (time weighted mean score on a composite scale 1–5) | ||||||||||||||
| ⩽3.5 | 35 | 15.3 | 33 | 16.9 | 1.0 | – | 16 | 14.8 | 1.0 | – | 13 | 22.0 | 1.0 | – |
| >3.5, <4.5 | 159 | 69.4 | 125 | 64.1 | 0.7 | 0.4–1.4 | 68 | 63.0 | 1.1 | 0.4–2.6 | 40 | 67.8 | 0.6 | 0.2 to 1.5 |
| ⩾4.5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| p for trend* | p = 0.23 | p = 0.71 | p = 0.15 | |||||||||||
| Working time arrangements (time weighted mean score on a scale 0–2) | ||||||||||||||
| 0 | 19 | 8.3 | 22 | 11.3 | 1.0 | – | 11 | 10.2 | 1.0 | – | 8 | 13.6 | 1.0 | – |
| >0, <0.5 | 151 | 65.9 | 119 | 61.0 | 0.8 | 0.3 to 1.8 | 64 | 59.3 | 0.8 | 0.3 to 2.4 | 40 | 67.8 | 0.4 | 0.1 to 1.4 |
| ⩾0.5 | 26 | 11.4 | 21 | 10.8 | 0.9 | 0.3 to 2.6 | 12 | 11.1 | 1.0 | 0.3 to 3.9 | 5 | 8.5 | 0.4 | 0.1 to 2.3 |
| p for trend* | p = 0.13 | p = 0.31 | p = 0.25 | |||||||||||
