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Occup Environ Med 61:1006-1013 doi:10.1136/oem.2003.009258
  • Original article

Symptoms and medical conditions in Australian veterans of the 1991 Gulf War: relation to immunisations and other Gulf War exposures

Table 5

 Association of Gulf War veterans’ total number of health symptoms with reported Gulf War exposures and experiences

Gulf War exposure Total number of health symptoms
n Mean (SD) Adj ratio of means* 95% CI
*Ratios of means are adjusted for service type, rank, age (<20, 20–24, 25–34, ⩾35 years), education, and marital status by negative binomial regression.
†Dose-response per unit increase in Military Service Experience questionnaire score (p<0.001).
‡170 subjects said they took pyridostigmine bromide tablets but did not know how many.
§Dose-response per categorical increase in number of pyridostigmine bromide tablets taken (p<0.001), number of days of anti-malarial tablets taken (p = 0.09), and number of days of anti-biological warfare tablets taken (p<0.001).
Deployment completed before air war on 17 January 1991
    Yes 331 13.3 (10.0) 1.0
    No 1089 15.1 (11.4) 1.1 1.0 to 1.2
MSE questionnaire score
    0–4 320 8.7 (7.4) 1.0
    5–8 414 11.5 (8.5) 1.3 1.2 to 1.5
    9–12 316 15.8 (10.1) 1.8 1.6 to 2.0
    >12 368 22.6 (12.5) 2.5 2.3 to 2.8
    Dose-response† 1.07 1.06 to 1.07
Pyridostigmine bromide
    None 371 11.2 (8.7) 1.0
    Any‡ 726 15.8 (11.7) 1.4 1.2 to 1.5
        1–80 tablets taken 152 14.3 (11.6) 1.3 1.1 to 1.5
        81–180 tablets taken 156 16.9 (12.0) 1.4 1.2 to 1.6
        >180 tablets taken 148 16.9 (12.5) 1.4 1.2 to 1.7
    Dose-response§ 1.1 1.1 to 1.2
    Don’t know 318 16.3 (11.6) 1.4 1.2 to 1.6
Antimalarials
    None 283 12.9 (10.1) 1.0
    Any 586 14.8 (11.6) 1.1 1.0 to 1.2
        1–30 days of tablets taken 191 13.0 (10.7) 1.0 0.8 to 1.1
        31–90 days of tablets taken 130 13.2 (10.7) 1.0 0.8 to 1.2
        >90 days of tablets taken 108 15.8 (10.7) 1.2 1.0 to 1.4
    Dose-response§ 1.0 1.0 to 1.1
    Don’t know 543 15.6 (11.1) 1.1 1.0 to 1.2
Anti-biological warfare tablets
    None 540 11.4 (9.6) 1.0
    Any 81 19.4 (13.6) 1.6 1.4 to 1.9
        1–30 days of tablets taken 25 16.4 (15.7) 1.4 0.9 to 2.0
        31–90 days of tablets taken 22 17.8 (8.4) 1.6 1.3 to 2.1
        >90 days of tablets taken 12 22.8 (12.7) 1.9 1.4 to 2.5
    Dose-response§ 1.3 1.2 to 1.4
    Don’t know 792 16.5 (11.3) 1.4 1.3 to 1.5
Pesticides
    No 1035 13.4 (10.4) 1.0
    Yes 366 18.5 (12.5) 1.3 1.2 to 1.4
Insect repellents
    No 862 14.1 (11.0) 1.0
    Yes 503 16.0 (11.4) 1.2 1.1 to 1.3
Chemical weapons area
    No 1252 14.1 (10.7) 1.0
    Yes 152 19.4 (13.0) 1.3 1.2 to 1.5
Depleted uranium
    No 1184 14.7 (11.2) 1.0
    Yes 218 14.2 (10.0) 1.0 0.9 to 1.1

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