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Occup Environ Med 61:908-914 doi:10.1136/oem.2004.012849
  • Original article

Daily variation in fine and ultrafine particulate air pollution and urinary concentrations of lung Clara cell protein CC16

Table 6

 Association between PM2.5 (lag 2) and urinary CC16; stratified analysis; percentage change (95% CI) in ln(CC16/creatinine) per 10 μg/m3 change in PM2.5

Amsterdam Erfurt Helsinki Pooled estimate
*Chronic respiratory disorder: asthma, COPD, chronic bronchitis, or emphysema, or a report of presence of cough, phlegm, or wheeze not associated with colds.
†na, not applicable.
‡p<0.001; §p<0.01.
¶Test for heterogeneity between centres, p<0.05.
**Test for heterogeneity between centres, p<0.01.
Male subjects 5.6 (−3.1 to 13.9) 0.8 (−3.7 to 5.2) 30.6 (14.2 to 47.0)‡ 9.9 (−2.8 to 22.6)¶
Female subjects −1.0 (−11.6 to 9.6) na 6.2 (−16.3 to 28.8) 0.3 (−9.2 to 9.8)
No environmental tobacco smoke at home 3.6 (−3.3 to 10.4) −0.4 (−5.2 to 4.4) 20.2 (6.9 to 33.6)§ 5.3 (−2.5 to 13.1)¶
Ex-smokers 4.5 (−2.5 to 11.4) −1.7 (−6.6 to 3.2) 30.6 (14.1 to 47.1)‡ 8.8 (−5.1 to 22.7)**
Never smokers na† 7.6 (−2.3 to 17.5) 6.8 (−15.6 to 29.3) 7.5 (−1.4 to 16.4)
Subjects with chronic respiratory disorder* 6.4 (−4.2 to 17.1) −2.1 (−9.9 to 5.8) 27.9 (11.9 to 43.9)‡ 8.9 (−4.2 to 22.0)**
Asthma na na 29.4 (−12.6 to 71.4) na

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