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Occup Environ Med 61:2-7
  • Original article

Mortality analyses in a cohort of 18 235 ethylene oxide exposed workers: follow up extended from 1987 to 1998

Table 8

Cox regression results for breast cancer mortality*

Analysis, exposure variable Model likelihood, df, p value† Coefficient (SE) Odds ratios by category‡
*There were 103 cases of breast cancer (ICD 9th 174, 175). In Cox regression, cases and controls were matched on age, race (white/non-white), and date of birth within five years.
†Model likelihood is difference in −2 log likelihoods between model with and without covariates; the only covariate in these models was exposure, so the p value of the model serves as a test of significance of the exposure coefficient, and as a test of exposure-response trend.
‡Categories for cumulative exposure are the same as in table 6.
Cumulative exposure 0.88, 1 df, p = 0.34 0.0000049 (0.0000048) na
Log cumulative exposure, 20 year lag 5.69, 1df, p = .01 0.084 (0.035) na
Categorical cumulative exposure lagged 20 years (quartiles) 8.69, 4 df, p = 0.07 na 1.00, 1.76 (0.91–3.43), 1.77 (0.88–3.56), 1.97 (0.94–4.06), 3.13 (1.42–6.92)

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