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Occup Environ Med 60:590-594 doi:10.1136/oem.60.8.590
  • Original article

Chromium (VI) induced oxidative damage to DNA: increase of urinary 8-hydroxydeoxyguanosine concentrations (8-OHdG) among electroplating workers

Table 5

Factors that affect the concentration of urinary 8-OHdG using multiple linear regression (n=67)

Variables 8-OHdG 
 (nM)
 β (SE) p value 8-OHdG 
 (pmol/kg/day)
 β (SE) p value
*Low urinary Cr: <1.13 μg/g cre. Moderate urinary Cr: 1.13–6.41 μg/g cre. High urinary Cr: >6.41 μg/g cre.
Gender (female = 0) 27.0 (15.2) 0.0803 1125.0 (699.9) 0.1167
Age (<27 years = 0) −0.16 (0.64) 0.8047 −16.5 (30.0) 0.5654
Smoking (yes = 0) −15.5 (16.5) 0.3540 33.3 (758.4) 0.9643
Alcohol (never = 0) 93.2 (22.9) 0.0003 4650.0 (1058.4) 0.0001
Common cold (no = 0) 40.9 (17.4) 0.0246 1153.2 (803.4) 0.1591
Urinary Cr concentration*
    Moderate (low = 0) −9.3 (13.5) 0.4973 −116.7 (153.3) 0.4632
    High (low = 0) 86.5 (22.5) 0.0004 774.9 (258.3) 0.0046
R2 0.6097 0.0001 0.6042 0.0001

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