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Occup Environ Med 60:315-321 doi:10.1136/oem.60.5.315
  • Original article

Temporal variation of hydroxyl radical generation and 8-hydroxy-2′-deoxyguanosine formation by coarse and fine particulate matter

Table 2

Hydroxyl radical generation, 8-OHdG formation in calf thymus DNA, and transition metal concentrations of fine and coarse PM sampled during six weeks in summer (period I) and six weeks in autumn/winter (period II)

Fine PM Period I* Period II* Coarse PM Period I* Period II*
*Mass of PM extracted from filters; †•OH generation determined by ESR; ‡relative induction of 8-OHdG.
All data are expressed as mean (SD), with the exception of 8-OHdG which is shown as median [25th–75th centile] rank.
§Significantly different from period I (p<0.05, t test).
Mass (mg)* 1.56 (0.56) 1.20 (0.37) 1.15 (0.38) 1.28 (0.43)
ESR (AU)† 20.1 (7.3) 21.1 (8.5) 29.2 (9.2) 54.6 (23.3)§
8-OHdG (rank)‡ 3.3 [2.1–6.5] 3.5 [1.8–5.9] 7.5 [5.9–10.3] 9.5 [8.8–12.0]
V (μg/g) 214 (91) 200 (100) 81 (60) 48 (57)
Cr (μg/g) 143 (47) 166 (56) 70 (71) 30 (12)
Fe (μg/g) 2724 (1197) 1752 (985) 1161 (1703) 239 (155)
Ni (μg/g) 130 (63) 192 (65) 105 (71) 92 (23)
Cu (μg/g) 429 (96) 287 (112)§ 570 (456) 582 (240)

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