Hydroxyl radical generation, 8-OHdG formation in calf thymus DNA, and transition metal concentrations of fine and coarse PM sampled during six weeks in summer (period I) and six weeks in autumn/winter (period II)
| Fine PM Period I* | Period II* | Coarse PM Period I* | Period II* | |
|---|---|---|---|---|
| *Mass of PM extracted from filters; †•OH generation determined by ESR; ‡relative induction of 8-OHdG. | ||||
| All data are expressed as mean (SD), with the exception of 8-OHdG which is shown as median [25th–75th centile] rank. | ||||
| §Significantly different from period I (p<0.05, t test). | ||||
| Mass (mg)* | 1.56 (0.56) | 1.20 (0.37) | 1.15 (0.38) | 1.28 (0.43) |
| ESR (AU)† | 20.1 (7.3) | 21.1 (8.5) | 29.2 (9.2) | 54.6 (23.3)§ |
| 8-OHdG (rank)‡ | 3.3 [2.1–6.5] | 3.5 [1.8–5.9] | 7.5 [5.9–10.3] | 9.5 [8.8–12.0] |
| V (μg/g) | 214 (91) | 200 (100) | 81 (60) | 48 (57) |
| Cr (μg/g) | 143 (47) | 166 (56) | 70 (71) | 30 (12) |
| Fe (μg/g) | 2724 (1197) | 1752 (985) | 1161 (1703) | 239 (155) |
| Ni (μg/g) | 130 (63) | 192 (65) | 105 (71) | 92 (23) |
| Cu (μg/g) | 429 (96) | 287 (112)§ | 570 (456) | 582 (240) |









