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Occup Environ Med 60:173-180 doi:10.1136/oem.60.3.173
  • Original article

Effect of trihalomethane exposure on fetal development

Table 9

Crude and adjusted odds ratios and 95% CI of preterm delivery for trimester specific and pregnancy average total trihalomethane (TTHM) exposure among all births

Preterm delivery
TTHM (μg/l) First trimester Second trimester Third trimester Pregnancy average
*Odds ratios adjusted for infant gender, adequacy of prenatal care, maternal race, maternal education, maternal smoking, maternal age, parity, median household income, previous infant weighing 4000 g or more, previous preterm delivery, and maternal medical history (diabetes, eclampsia, hydramnios, chronic hypertension, hypertension during pregnancy, incompetent cervix, lung disease, renal disease, and uterine bleeding).
Crude OR (95% CI)
    0–60 1.0 1.0 1.0 1.0
    >60–80 0.97 (0.86 to 1.10) 1.03 (0.91 to 1.17) 1.00 (0.88 to 1.13) 0.90 (0.80 to 1.01)
    >80 1.00 (0.88 to 1.13) 0.92 (0.81 to 1.04) 1.01 (0.89 to 1.14) 0.93 (0.85 to 1.01)
Adjusted OR (95% CI)*
    0–60 1.0 1.0 1.0 1.0
    >60–80 0.96 (0.84 to 1.10) 1.02 (0.89 to 1.16) 0.99 (0.87 to 1.13) 1.00 (0.89 to 1.12)
    >80 1.01 (0.88 to 1.16) 0.90 (0.79 to 1.03) 0.97 (0.85 to 1.11) 0.90 (0.77 to 1.04)

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