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Occup Environ Med 58:461-466 doi:10.1136/oem.58.7.461
  • Paper

Mortality from cardiovascular diseases and exposure to inorganic mercury

Table 4

Mortality from cardiovascular and kidney diseases by time since first exposure, duration of employment, and estimated cumulative exposure among men

Cause of death4-150
Hypertension Ischaemic heart disease Cerebrovascular diseases Other diseases of the heart Nephritis, nephrosis
Time since first exposure (y):
 1–19:4-151
  Obs 3 29 13 7 7
  RR 1.0 1.0 1.0 1.0 1.0
  95% CI
 20–29:
  Obs 8 58 34 43 5
  RR 3.0 1.3 1.7 4.2 0.4
  95% CI 0.7 to 13.3 0.8 to 2.3 0.8 to 3.5 1.7 to 10.1 0.1 to 1.9
 ⩾30
  Obs 38 172 214 221 34
  RR 5.0 1.9 2.9 6.7 0.9
  95% CI 1.0 to 24.4 1.1 to 3.5 1.3 to 6.1 2.7 to 16.5 0.2 to 4.4
 Trend4-152 0.05 0.02 <0.01 <0.01 0.7
Duration of employment (y):
 1–9:4-151
  Obs 7 44 34 36 5
  RR 1.0 1.0 1.0 1.0 1.0
  95% CI
 10–19:
  Obs 10 72 37 39 7
  RR 0.9 1.5 1.4 1.0 3.3
  95% CI 0.3 to 2.9 0.9 to 2.5 0.8 to 2.5 0.6 to 1.7 0.8 to 13.0
 20–29:
  Obs 12 95 80 96 13
  RR 0.5 1.7 1.4 1.0 4.7
  95% CI 0.1 to 2.2 0.9 to 3.0 0.7 to 2.6 0.6 to 1.9 0.9 to 24.7
 ⩾30
  Obs 20 48 110 100 21
  RR 0.7 1.9 2.2 1.1 9.1
  95% CI 0.1 to 3.3 0.9 to 4.0 1.1 to 4.5 0.6 to 2.2 1.6 to 52.6
 Trend4-152 0.6 0.1 0.02 0.6 0.01
Estimated cumulative exposure (μg/l urine-years):
 1–2000:4-151
  Obs 5 40 35 38 7
  RR 1.0 1.0 1.0 1.0 1.0
  95% CI
 2001–5000:
  Obs 10 96 44 46 6
  RR 1.3 1.2 0.7 0.9 0.2
  95% CI 0.3 to 4.7 0.8 to 2.0 0.4 to 1.2 0.5 to 1.5 0.05 to 1.0
 5001–7000:
  Obs 11 53 60 66 11
  RR 1.4 0.9 0.7 1.1 0.3
  95% CI 0.3 to 6.0 0.5 to 1.6 0.4 to 1.4 0.6 to 2.0 0.05 to 1.1
 >7000:
  Obs 23 70 122 121 22
  RR 1.7 1.0 0.7 1.2 0.2
  95% CI 0.4 to 7.3 0.6 to 1.9 0.4 to 1.4 0.7 to 2.1 0.05 to 0.9
 Trend4-152 0.5 0.8 0.6 0.3 0.2
  • Obs=number of observed deaths; RR=relative risk adjusted for age, country, calendar period, time since first employment, and the variables in the table.

  • 4-150 See table 2 for ICD-9 codes.

  • 4-151 Reference category.

  • 4-152 p Value of test for linear trend.

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