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Occup Environ Med 58:145-153 doi:10.1136/oem.58.3.145
  • Review

Relation between exposure to asbestos and smoking jointly and the risk of lung cancer

Table 10

Summary statistics for cohort and occupational studies (group B)

Study (ref)2-150 Asbestos RR (95% CI)
in non-smokers
Test of
additivity U
Test of multiplicativity V (95% CI) Deviance Fitted effects (multiplicative model)
A S AS
Neuberger and Kundi2-151 30 ≃1.00
McDonald et al 24 4.07  (2.03  to  7.29) 0.93 0.38  (0.21  to  0.79) 10.12 1.63 [7.13] 11.64
Berryet al (1960–70)1 5.00  (0.13 to  27.9) 10.47 0.61  (0.10 to  25.7) 0.25 3.06 [7.13] 21.80
Berryet al (1971–80):1
 Men 0.16 2.70 [7.13] 19.24
 Women 0.32  (0.09 to  1.75) 3.51 5.52 [7.13] 39.40
 Combined 11.5  (2.38 to  33.7) 2.65
Achesonet al 27 6.06  (0.15 to  33.8) 3.33 0.36  (0.06 to  14.7) 0.36 2.25 [7.13] 16.02
Oksaet al:31
 Asbestos sprayers 0.00 68.64 0.16 9.96 [7.13] 71.04
 Patients with asbestosis 0.00 75.59 1.03 11.11 [7.13] 79.20
 Patients with silicosis 0.00 16.21 0.52 3.03 [7.13] 21.60
Meurman et al 28 3.21  (0.08 to  17.8) 14.53 1.05  (0.18 to  46.4) 0.00 3.34 [7.13] 23.85
Elmes and Simpson32 0.00 106.8 0.00 15.83 [7.13] 112.9
Hughes and Weill33 0.00 ≃7 Low ≃2 [7.13] ≃14
Selikoff et al 34 25.00  (8.12 to  58.3) 2.31 0.19  (0.07 to  0.61) 15.85 5.10 [7.13] 36.39
Selikoff and Hammond35 8.44  (1.02 to  30.5) 59.14 1.22  (0.32 to  10.4) 0.08 10.24 [7.13] 73.01
Hammondet al 36 5.71  (1.56 to  14.6) 38.22 0.95  (0.47 to  2.21) 0.02 4.91 [10.85] 53.37
  • 2-150 First author of most papers on study; reference is to paper from which main results were obtained.

  • 2-151 Most summary statistics cannot be estimated from the graphical data presented.

  • Values in [ ] are assumed values taken from external data.

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