Table 5
Association between hepatic biochemical function measurements5-151 and continuous air concentrations of styrene for pooled data from study 1 and study 2
| Hepatic biochemical marker‡ | Partial regression coefficients | |||||
|---|---|---|---|---|---|---|
| Air styrene | Age | Sex | BMI | Alcohol | R2 | |
| AST (IU/ml) | 0.225-165 | 0.465-150 | 10.275-160 | −0.19 | 0.23 | 0.27 |
| ALT (IU/ml) | 0.525-165 | 1.325-150 | 15.155-160 | 0.34 | 0.39 | 0.27 |
| GGT (IU/ml) | 0.05 | 1.265-165 | 14.755-160 | −0.02 | 1.08 | 0.34 |
| AP (IU/ml) | 0.12 | 0.30 | 9.44 | −0.08 | 0.35 | 0.12 |
| Direct bilirubin (mg/dl) | 0.00075-150 | −0.0005 | 0.03 | −0.003 | 0.003 | 0.18 |
| Direct/total bilirubin ratio | 0.0005 | 0.001 | 0.095-160 | −0.0075-150 | 0.0075-150 | 0.26 |
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↵5-150 p<0.05;
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↵5-160 p<0.01;
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↵5-165 p<0.001.
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↵5-151 From multiple linear regression models regressing hepatic biochemical function measurement on continuous air concentrations of styrene (ppm), age (y), sex (male), body mass index, and alcohol consumption (g/week).
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ALT=alanine aminotransferase; AST=aspartate aminotransferase; AP=alkaline phosphatase; GGT=γ-glutamyl transferase.
