Urinary 1-hydroxypyrene in coke oven workers relative to exposure, alcohol consumption, and metabolic enzymes

Table 4

Multiple regression analysis for the effect of several selected variables on urinary 1-OHP excretion in coke oven workers (n=127, R=0.66, p<0.0001)

Variables	Standard regression coefficient	SEM	t Value	p Value
Intercept	0.72	0.25	2.87	<0.01
PAH exposure concentration	0.61	0.03	8.54	<0.0001
Employment time	0.19	<0.01	2.60	0.01
Urinary cotinine	0.07	0.03	0.96	0.34
Alcohol consumption^4-150	0.16	0.06	2.24	0.03
CYP1A1 polymorphism^4-151	0.17	0.12	2.34	0.02
GSTT1 polymorphism^4-152	0.13	0.06	1.85	0.07