Wild, Pascal; Perdrix, Alain; Romazini, Sylvie; Moulin, Jean-Jacques; Pellet, François

Table 6

Lung cancer by duration of exposure to unsintered hard metal dust,¹ exposure to sintered hard metal dust² and IARC carcinogens according to the job exposure matrix among males

Unsintered	Sintered	Observed	Expected	SMR	95% CI
Not exposed to any IARC carcinogen:
Non-exposed	Non-exposed	7	6.13	1.14	0.46 to 2.35
<10 y	Non-exposed	2	0.97	2.06	0.25 to 7.45
10–19 y	Non-exposed	2	0.53	3.77	0.46 to 13.63
⩾20 y	Non-exposed	1	0.25	4.00	0.10 to 22.29
Total exposed	Non-exposed	5	1.75	2.86	0.92 to 6.67
Non-exposed	Exposed	3	2.64	1.14	0.23 to 3.32
<10 y	Exposed	1	1.83	0.55	0.01 to 3.04
10–19 y	Exposed	2	1.19	1.68	0.20 to 6.07
⩾20 y	Exposed	2	0.87	2.30	0.28 to 8.30
Total exposed	Exposed	5	3.89	1.29	0.41 to 3.00
Exposed to any IARC carcinogen:
Non-exposed	Non-exposed	13	8.10	1.60	0.85 to 2.74
<10 y	Non-exposed	2	1.00	2.00	0.24 to 7.22
10–19 y	Non-exposed	2	0.19	10.53	1.27 to 38.02
⩾20 y	Non-exposed	0	0.06	0.00	0.00 to 61.13
Total exposed	Non-exposed	4	1.25	3.20	0.87 to 8.19
Non-exposed	Exposed	1	0.46	2.17	0.05 to 12.11
<10 y	Exposed	4	1.58	2.53	0.69 to 6.48
10–19 y	Exposed	3	0.95	3.16	0.65 to 9.23
⩾20 y	Exposed	1	0.37	2.70	0.07 to 15.06
Total exposed	Exposed	8	2.90	2.76	1.19 to 5.44
Poisson regression		RR	95 % CI
Ever smoker vnon-smoker		1.58	0.69 to 3.63
Unknownv non-smoker		0.86	0.32 to 2.25
Exposure to any IARC carcinogen^6-152 (yesv no)		1.48	0.81 to 2.68
Exposure to sintered hard metal dust (yesv no)		0.75	0.37 to 1.53
By recoded duration of exposure to unsintered hard metal dust^6-153		1.43	1.03 to 1.98

6-150 Consisting of simultaneous exposure to cobalt and tungsten carbide before sintering.
6-151 Consisting of simultaneous exposure to cobalt and tungsten carbide after sintering.
↵6-152 Asbestos, PAH, silica, nickel, chromium compounds.
↵6-153 Non-exposed=1; <10 y=2; 10–20 y=3; >20 y=4.

Lung cancer mortality in a site producing hard metals

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