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Occup Environ Med 57:376-384 doi:10.1136/oem.57.6.376
  • Paper

Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma

Table 4

Wood dust exposure concentration, duration and cumulative exposure relative to risk of nasopharyngeal cancer 4-150

Exposure to wood dust Controls
(n=244)
n
Cases
(n=142)
n
Adjusted for formaldehyde
No OR4-151
(95% CI)
Yes OR4-152
(95% CI)
Unexposed 220 125 1.0 (reference) 1.0 (reference)
Ever exposed  24  17 1.5 (0.7 to 3.3) 1.2 (0.5 to 2.7)
Maximum exposure (mg/m3):
 >0.0–0.55  15  10 1.7 (0.7 to 4.4) 1.3 (0.5 to 3.6)
 >0.55–1.50   4   6 2.5 (0.6 to 10.2) 2.0 (0.5 to 8.1)
 >1.50   5   1 0.3 (0.0 to 3.2) 0.2 (0.0 to 2.1)
 Trend test p=0.76 p=0.68
Duration (y):
 1–4  12   8 1.5 (0.5 to 4.2) 1.4 (0.5 to 4.4)
 5–13   6   4 1.4 (0.3 to 5.6) 1.3 (0.3 to 5.4)
 ⩾14   6   5 1.8 (0.5 to 7.3) 0.8 (0.2 to 3.7)
 Trend test p=0.27 p=0.74
Cumulative exposure (mg/m3-years):
 >0.0–2.75  13   5 0.9 (0.3 to 3.0) 0.7 (0.2 to 2.5)
 >2.75–15.70   5  10 3.9 (1.2 to 12.5) 3.0 (0.9 to 9.8)
 >15.70   6   2 0.6 (0.1 to 3.7) 0.4 (0.1 to 2.3)
 Trend test p=0.42 p=0.99
  • 4-150 Excluding undifferentiated and non-keratinising histologies.

  • 4-151 OR adjusted for age, sex, race, SEER site, cigarette use, proxy status, and education.

  • 4-152 OR also adjusted for cumulative exposure to formaldehyde with the log transformed continuous measure and including jobs with possible or higher probabilities of exposure.

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