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Occup Environ Med 57:668-672 doi:10.1136/oem.57.10.668
  • Paper

Low level exposure to cadmium and early kidney damage: the OSCAR study

Table 3

Tubular proteinuria (defined as excreting protein HC >0.8 and 0.6 mg/mmol creatinine, for men and women, respectively) in people exposed to cadmium

Urinary Cd (nmol/mmol creatinine) Mean urinary Cd (nmol/mmol creatinine) Environmentally exposed people cases/total (prevalence %)
(missing, n=17)
Occupationally exposed people cases/total (prevalence %)
(missing, n=3)
Total population cases/total
(prevalence %)
OR, total (95% CI)
(test for trend, p<0.001)
OR, environmentally exposed people
(95% CI)
(test for trend, p=0.001)
<0.3 0.21 12/252 (4.8) 1/13 (7.7) 13/265 (4.9) 1.0 1.0
0.3–<0.5 0.38 33/243 (14) 4/30 (13) 37/273 (14) 1.8 (0.9 to 3.5) 2.5 (1.1 to 5.5)
0.5–<1 0.69 60/232 (26) 8/66 (12) 68/298 (23) 2.7 (1.4 to 5.3) 4.3 (1.9 to 11)
1–<2 1.4 22/53 (42) 10/55 (18) 32/108 (30) 3.6 (1.7 to 7.6) 7.5 (3.5 to 44)
2–<3 2.5 1/1 (100) 7/23 (30) 8/24 (33) 4.0 (1.4 to 12)
3–<5 3.8 0/1 (0) 7/20 (35) 7/21 (33) 4.7 (1.6 to 14)
⩾5 6.8 — (—) 6/12 (50) 6/12 (50) 6.0 (1.6 to 22)
  • Analyses were missing for 20 people.

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