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Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
  1. R McConnell,
  2. K Anderson,
  3. W Russell,
  4. K E Anderson,
  5. R Clapp,
  6. E K Silbergeld,
  7. P J Landrigan
  1. Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York 10029.

    Abstract

    A worker developed angiosarcoma, porphyria cutanea tarda, and skin lesions characteristic of mild chloracne. About 10 years earlier he had been employed at a truck terminal in Saint Louis, Missouri, at a time when it was sprayed with waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The occurrence of these three rare conditions in a single exposed worker supports the aetiological relation between environmental exposure to TCDD and the subsequent development of soft tissue sarcoma and porphyria cutanea tarda.

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