Article Text

PDF

Observations on the effects on rats of compounds related to acrylamide
  1. J. M. Barnes
  1. Medical Research Council Toxicology Unit, Carshalton, Surrey

    Abstract

    Barnes, J. M. (1970).Brit. J. industr. Med.,27, 147-149. Observations on the effects on rats of compounds related to acrylamide. Nine compounds (Table), close chemical relations of acrylamide, were given to adult rats both in their diet and as repeated daily doses by mouth. Dose rates were such that with acrylamide acute poisoning and neuropathy would have resulted. Seven of the compounds were without effect. N-methylacrylamide and N-hydroxymethylacrylamide produced some neurotoxic effects in large doses. The presence of acrylamide as an impurity in the compound tested was not excluded.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.