The excretory pattern of coproporphyrin I and III isomers has been studied in urine from nine health subjects and 10 lead-exposed workers with no clinical evidence of lead poisoning.
In normal urine it was found that coproporphyrin I exceeded coproporphyrin III, whereas in lead workers coproporphyrin III predominated, although this was accompanied by an increase in the absolute amount of coproporphyrin I, indicating active haemopoiesis in lead absorption.
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