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Occupational and Environmental Medicine 2008;65:575-576
Copyright © 2008 by the BMJ Publishing Group Ltd.

POSTSCRIPT

Letters

The effect of shift work on ischaemic heart disease

G Yadegarfar1, R McNamee2

1 Department of Biostatistics and Epidemiology, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
2 School of Epidemiology and Health Sciences, Manchester University, Manchester, UK

Correspondence to:
G Yadegarfar, Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Hezar-Jerib Road, Isfahan, Iran; g_yadegarfar@yahoo.co.uk

The first 150 words of the full text of this article appear below.

We would like to clarify some of the issues raised by Professor Knutsson (Occup Environ Med 2008;65:152) in his recent commentary concerning our article "Shift work, confounding and death from ischaemic heart disease".1 Firstly, it is not true that previously "a similar study was carried out at the same factory". As we state in our article, the subjects of the present study were from a different cohort from that investigated by McNamee et al2 in 1996. The cohorts of the two studies had the same employer but correspond to two different factory sites approximately 100 miles apart. Thus, the recent study provides new evidence which is independent of the 1996 publication.

We agree with Professor Knutsson that one should not adjust for intermediate variables that might lie on the causal chain between shift work and outcome. In our article we noted that such adjustments would be . . . [Full text of this article]


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Shift work and ischaemic heart disease
Anders Knutsson
Occup. Environ. Med. 2008 65: 152. [Extract] [Full Text] [PDF]

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