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Occupational and Environmental Medicine 2007;64:3-4; doi:10.1136/oem.2006.029512
Copyright © 2007 by the BMJ Publishing Group Ltd.

COMMENTARY

Death stroked by dusty air: more mysteries to be solved

J-C Chen

Correspondence to:
Correspondence to:
Dr J-C Chen
Department of Epidemiology, UNC-CH, School of Public Health, 2104G, McGavran-Greenberg, CB#7435, Chapel Hill, NC 27599-7435, USA; jcchen@unc.edu


Commentary on the paper by Yamazaki et al (see page 17)

The first 150 words of the full text of this article appear below.

After several reports in the early 1990s showing excessive mortality associated with unexpectedly low concentrations of particulate matter, substantial research efforts have been devoted to investigating particulate matter health effects and elucidating the related pathophysiological mechanism. Despite remaining knowledge gaps, epidemiological and toxicological studies have provided reasonably coherent evidence supporting the significance of particulate matter-mediated acute cardiovascular effects.1 Among the mounting volume of literature on air pollution epidemiology, multi-city ecological studies using time-series or case-crossover analyses have reported fairly consistent associations between increased concentrations of particulate matter over short periods of one or several days and increased cardiovascular mortality and morbidity (eg, hospitalisations and emergency visits). However, scientific data linking air pollution to stroke, including ischaemic stroke and intracerebral haemorrhage (ICH), remain relatively scant and inconclusive.2

In this issue, Yamazaki et al3 present a case-crossover study examining the acute effect of particles on mortality from stroke among elderly people (aged >=. . . [Full text of this article]


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Relevant Article

Intracerebral haemorrhage associated with hourly concentration of ambient particulate matter: case-crossover analysis
S Yamazaki, H Nitta, M Ono, J Green, S Fukuhara
Occup. Environ. Med. 2007 64: 17-24. [Abstract] [Full Text] [PDF]

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