Introduction

Top Introduction Ultrafine particles Importance of ultrafine... Susceptibility to PM10 Ultrafine particles and the... Overload of inhaled ultrafine... Non-overload studies Importance for exposure... Mechanism of proinflammatory... Summary References

There is a long history of disease caused by inhaled particles that stretches from Agricola and Paracelsus in the 14th century up to the present.¹ In this century the twin scourges of asbestos and crystalline silica (quartz) have exerted a terrible toll of death and disease. The bad old days when these dust related lung diseases were unbridled are gone but as we enter the 21st century a new particle typethe ultrafine particle. . . [Full text of this article]

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