© 2003 BMJ Publishing Group
CASE REPORT
Occupational asthma from fungicides fluazinam and chlorothalonil
1 Department of Occupational & Environmental Medicine, Royal Brompton Hospital & NHLI, 1b Manresa Road, London SW3 6LR, UK
2 Syngenta International AG, WRO 1007.1.37, Werk Rosental, Schwarzwaldallee 215, CH-4025 Basel, Switzerland
Correspondence to:
Correspondence to:
Dr A Draper, Chest Clinic, St George's Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK;
adrian{at}adraper.freeserve.co.uk
We report two cases of occupational asthma caused by sensitisation to powdered fungicides fluazinam and chlorothalonil, from the same fungicide formulation plant. Both developed work related lower respiratory symptoms after a latent interval of asymptomatic exposure. The diagnosis in each case was confirmed with a serial peak flow record in the workplace followed by specific inhalation tests. These fungicides are known to cause dermatitis; this report indicates that these compounds can induce specific immunological reactions in the airways as well as skin.
Keywords: occupational asthma; fungicide; fluazinam; chlorothalonil
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