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Occupational and Environmental Medicine 2002;59:217-223; doi:10.1136/oem.59.4.217
Copyright © 2002 by the BMJ Publishing Group Ltd.
Occupational and Environmental Medicine 2002;59:217-223
© 2002 Occupational and Environmental Medicine

REVIEW

Neurobehavioural testing in workers occupationally exposed to lead: systematic review and meta-analysis of publications

M Goodman1, N LaVerda1, C Clarke2, E D Foster1, J Iannuzzi1, J Mandel3

1 Exponent Health Group, Alexandria, VA, USA
2 Johns Hopkins University School of Public Health, Baltimore, MD, USA
3 Exponent Health Group, Menlo Park, CA, USA

Correspondence to:
Correspondence to:
Dr M Goodman, Exponent Health Group, 1800 Diagonal Road, Suite 355, Alexandria, Virginia 22314, USA;
mgoodman{at}exponent.com

ABSTRACT

Although the toxic effects of lead on the central nervous system have been well described, the blood concentration at which lead begins to exert adverse effects remains the focus of debate. A meta-analysis of occupational studies was conducted evaluating the association between neurobehavioural testing results and moderate blood lead concentrations.

Keywords: lead; epidemiology; meta-analysis; neurobehavioural testing

Abbreviations: PNS peripheral nervous system; CNS, central nervous system; ATSDR, Agency for Toxic Substances and Disease Registry


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  • Chia, S-E, Yap, E, Chia, K-S (2004). Can {delta}-aminolevulinic acid dehydratase 2 allele exert certain protective measures against the neurotoxic effects of lead?. Occup. Environ. Med. 61: 720-720 [Full Text]  
  • Seeber, A, Meyer-Baron, M, Goodman, M, LaVerda, N, Clarke, C, Foster, E, Iannuzzi, J, Mandel, J (2003). Neurobehavioural testing in workers occupationally exposed to lead * Authors' reply. Occup. Environ. Med. 60: 145-146 [Full Text]  
  • Schwartz, B S, Stewart, W, Hu, H (2002). Neurobehavioural testing in workers occupationally exposed to lead. Occup. Environ. Med. 59: 648-649 [Full Text]  

eLetters:

Read all eLetters

Letter to the editor concerning Goodman et al.
Andreas Seeber, et al.
Occup Environ Med Online, 2 May 2002 [Full text]
Critique of Goodman et al.:Lead and neurobehavioral test scores in adults
Brian S Schwartz, et al.
Occup Environ Med Online, 8 May 2002 [Full text]
Re: Critique of Goodman et al.: lead and neurobehavioral test scores in adults
Michael Goodman, et al.
Occup Environ Med Online, 28 May 2002 [Full text]
TABLE for Re: Critique of Goodman et al.
Michael Goodman, et al.
Occup Environ Med Online, 28 May 2002 [Full text]

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